Description
Existing disease-specific quality of life (QoL) scales do not directly assess QoL or the perceived impact of the disease on QoL. The purpose of this study is to evaluate the properties (reliability, concurrent and longitudinal validity, and responsiveness to change in asthma status) of a new measure of the patient-perceived negative effects of asthma in adults, the Asthma Impact on Quality of Life Scale (A-IQOLS), and to compare its properties with those of a measure of current QoL, the Flanagan Quality of Life Scale (QOLS). The hypothesis is that the approach represented by the A-IQOLS will prove superior to that of the QOLS as an outcome measure for clinical research purposes. This research can fill a significant gap in the currently available tools, with consequent benefit to clinical research and measurement of patient-centered outcomes in other disease areas.
PI is Sandra Wilson, PhD. PAMF Co-Investigators: Michael Mulligan; MD, Alan Chausow, MD; Estela Ayala, MD. Outside Co-Investigators: Robert Wise, MD, Johns Hopkins University Schools of Medicine and Public Health; Mario Castro, MD, Washington University School of Medicine.
PI is Sandra Wilson, PhD. PAMF Co-Investigators: Michael Mulligan; MD, Alan Chausow, MD; Estela Ayala, MD. Outside Co-Investigators: Robert Wise, MD, Johns Hopkins University Schools of Medicine and Public Health; Mario Castro, MD, Washington University School of Medicine.
Funder
National Heart, Lung and Blood Institute/National Institutes of Health
Research Topics
Related Studies
Can diet- and exercise-induced weight loss improve asthma control in obese adults?
This trial investigates the efficacy of a state-of-the-art behavioral weight loss intervention in improving asthma control for obese adult patients.
A Pilot Study of the DASH Diet in Not-Well-Controlled Adult Asthma
This study evaluates the feasibility and potential efficacy of adopting the DASH eating pattern to improve asthma control among adults with uncontrolled asthma.
Sub-study of Mechanisms Linking Weight Gain/Loss and Asthma
Characterize BE WELL asthmatic subjects in atopy phenotype and serum periostin and 8-isoprostane levels in exhaled breath condensate.